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Home Learn Learn About Grape Seed Extract in 5 Minutes


Home Learn Learn About Grape Seed Extract in 5 Minutes

Learn About Grape Seed Extract in 5 Minutes

Table of contents

What is grape seed extract?

Grape Seed Extract is a derivative of whole grape seeds. The two beneficial components of grape seed extract (GSE) are polyphenols and proanthocyanidins. Polyphenols are powerful antioxidants, and proanthocyanidins help defend the integrity of your blood vessels.

  • Polyphenols are powerful antioxidants that fight back against lots of diseases
  • The proanthocyanidins in grape seed extract has extra benefits
  • Proanthocyanidins strengthen your veins and lower your blood pressure
  • Grape seed extract gives you the benefits of red wine without the detractors
  • GSE also contains bioflavonoids for increased effectiveness

Why we love grape seed extract

Polyphenols, also known as phenolic acids, are present in berries, fruits, nuts, and a variety of other plant sources. These micronutrients have profound antioxidant qualities, and they might improve digestion, fight diabetes, and prevent neurodegenerative and cardiovascular diseases.

Grape seed extract (GSE) is one of the best sources of many polyphenols, and this natural substance is one of the most widely noted sources of proanthocyanidins. The much-touted health benefits of red wine come from the presence of proanthocyanidins in this alcoholic beverage, and these powerful polyphenols help your body maintain capillaries and prevent hypertension. When you remember to take Feel every day, you get all the benefits of red wine without the hangover.

Unbelievable benefits of grape seed extract

GSE is one of the most popular nutrients right now, and as soon as we heard about the benefits of this polyphenol powerhouse, we knew that we had to include it in Feel. Here are some of the incredible ways that proanthocyanidins and other parts of grape seed extract can improve your health:

Antioxidant Benefits

Polyphenols are some of the most powerful antioxidants that science has discovered, and these substances protect the tissues throughout your body from the dangers of free radicals. Specifically, scientists have found that the antioxidants in grape seed extract can protect the tissues in your heart, brain, and other organs.

Cardiovascular Benefits

The ability of GSE to treat high blood pressure is well-established. Some research indicates that ingesting this fruit-based oil may reduce your blood pressure by as much as 5 percent over six weeks.

GSE appears to thin your blood, which could reduce your risk of blood clots. These blockages in your cardiovascular system can cause dangerous conditions like strokes and heart attacks. Scientists demonstrated this beneficial effect by showing that subjects who supplemented with grape seed extract experienced less leg swelling after sitting.

Grape Seed Extract is thought to maintain heart, cardiovascular, and blood vessel health, which is why we've included 50mg in Feel Multivitamin

Bone Strength Benefits

In addition to polyphenols, grape seed extract also contains bioflavonoids, which boosts your bone strength. Research shows that GSE improves bone density and mineral content.

Skin Benefits

Grape seed extract appears to cause powerful skin benefits. This natural substance improves sebum production, skin appearance, and skin elasticity. All these effects would reduce the symptoms of skin conditions like acne and rosacea, and GSE may even reduce the effects of ageing.

This extract also appears to increase collagen levels throughout your body, which benefits your skin health. The more collagen you have in your skin, the plumper it will look, and the better it will feel.

Grape Seed Extract contains antioxidants which can help protect cells from free radical damage, perfect for maintaining the health of the skin. That's why we've included 100mg of Grape Seed Extract in Feel Beauty Probiotic+

Neurological Benefits

Since neurodegenerative conditions like Alzheimer’s disease may be caused by oxidative stress and inflammation, the flavonoids in GSE might protect your brain from age-related brain diseases. A wide array of studies provide evidence that GSE has antioxidant properties that improve cognition and prevent memory loss.

Other Benefits

There’s compelling evidence that grape seed extract accelerates wound healing. Scientists speculate that the tissue growth-inducing benefits of proanthocyanidins cause this effect.

Is grape seed extract water-soluble or fat-soluble?

Polyphenols are water-soluble, and proanthocyanidins are both water-soluble and fat-soluble. Therefore, your body rapidly absorbs and excretes polyphenols, but it stores proanthocyanidins slightly longer.

Where can grape seed extract be found naturally? Common sources of grape seed extract:

The only source of grape seed extract is in the seeds of grapes. All types of grapes contain grape seed extract, and every form of this fruit contains roughly equal quantities of proanthocyanidins and polyphenols. It’s important to point out, however, that seedless grapes do not contain grape seed extract.

5 foods/drinks containing grape seed extract

1. Concord grapes

2. Pinot noir grapes

3. Champagne grapes

4. Kyoho grapes

5. White grapes

What is the recommended daily intake for grape seed extract?

Since grape seed extract is not considered to be an essential nutrient, no relevant regulatory agency has determined a recommended daily amount (RDA) for grape seed extract. However, clinical trials of grape seed extract’s effectiveness have been performed with daily doses as low as 150mg or as high as 2000mg.

Can you absorb enough of grape seed extract from food?

It is practically impossible to absorb enough grape seed extract from food. If you’re like most people, you spit out the seeds of the grapes you eat, and you’re probably more likely to grab a bag of seedless grapes than a bag of grapes with seeds in the first place. Therefore, it’s necessary to consume grape seed extract in a supplement form to experience its benefits.

Why is grape seed extract necessary for your body?

Your body needs antioxidants to balance out the levels of free radicals in your system. In addition, the proanthocyanidins in GSE protect your blood vessels and improve your cardiovascular health.

Functions of grape seed extract

  • Antioxidant functions: Polyphenols are some of the most powerful antioxidants available, and these substances improve your cellular integrity and longevity
  • Cardiovascular functions: Proanthocyanidins reduce your blood pressure, which reduces strain on your heart, and they also improve the strength of your capillaries, veins, and arteries
  • Flavonoid functions: GSE also contains bioflavonoids, which have antioxidant functions and improve the effectiveness of vitamin C

Symptoms of grape seed extract deficiency


Deficiency in antioxidants, such as polyphenols, results in fatigue. Additionally, you age faster when you don’t have enough antioxidants in your system, and you become more prone to inflammation and disease.

Delayed wound healing

Lack of antioxidants prevents your wounds from healing properly. Antioxidants are critically involved in the process of cell reproduction, and without these beneficial compounds, your body will have a hard time making enough new cells to repair wounds.


Proanthocyanidins prevent high blood pressure, which means that failing to consume recommended quantities of these substances may result in hypertension.

How long do you need to take grape seed extract to start experiencing its benefits?

In most cases, the effects of grape seed extract set in almost immediately. Since GSE is not an essential nutrient, it is not technically possible to be deficient in this substance, but this beneficial extract can address low levels of antioxidants and hypertension within 24 hours or less.

Consistency is key and our research recommends taking your Feel supplements for at least 3 months to allow your body to adjust and provide the desired benefits

How long does it take for your body to digest/absorb grape seed extract?

Research indicates that absorption rates for GSE may increase with repeated dosing. Authoritative bioavailability data on grape seed extract are not available, but clinical trials suggest that it may be possible to absorb as much as 700mg of this substance within a 24-hour period.

How long does grape seed extract stay in your body after you take it?

Since the polyphenols in grape seed extract are water-soluble, they generally exit the body within 24 hours. Since proanthocyanidins are either water-soluble or fat-soluble, they may remain in the body for a significantly longer period of time.

Is grape seed extract an antioxidant?

Yes, the polyphenols in grape seed extract are among the most powerful antioxidants that science has discovered. They reduce the damage caused by free radicals and promote DNA health and proper cell replication.

Can you overdose on grape seed extract? What are the effects?

It does not appear to be possible to overdose on grape seed extract; in the event of severe overdose, your body should excrete this substance within 24 hours. If you have a bleeding disorder, however, ingesting high levels of grape seed extract may exacerbate your condition.

Does grape seed extract dissolve, flush out, or build up in the body?

Most of the components of GSE flush out of your system within 24 hours, but proanthocyanidins may remain in your system for significantly longer.

Can you take grape seed extract during a diet?

There’s no reason you shouldn’t take grape seed extract when you’re observing a diet. If you are on a no-fruit diet, you can take this substance in supplement form.

Are there synthetic forms of grape seed extract?

At present, there are no synthetic forms of grape seed extract. While there are synthetic forms of grapefruit seed extract, these two substances are completely different.

Why might synthetic forms of grape seed extract be better?

Theoretically, a synthetic form of grape seed extract may be more desirable from an economic standpoint.

Absorption rate of synthetic grape seed extract

While a synthetic form of GSE would not have higher absorption rates, it might have lower absorption rates.

Why might natural forms of grape seed extract be better?

Natural grape seed extract provides all the benefits of red wine without intoxication or hangover symptoms. While it’s impossible to be sure, it’s likely that natural grape seed extract would have a better absorption rate that a synthetic form of this substance.

How to take grape seed extract

It is best to take grape seed extract as a supplement unless you relish the idea of chewing up and swallowing tons of grape seeds.

Why everyone should be taking WeAreFeel supplements

Most supplement producers overlook the incredible benefits of grape seed extract, but here at WeAreFeel, we make sure that you get a solid dose of this substance every day with our revolutionary multivitamin. Unlike most antioxidant substances, GSE has effects that span far beyond mere cell protection; by taking a daily dose of Feel, you can enjoy all the effects of red wine or grape seeds without getting a hangover or leaving the bad taste of grape seeds in your mouth!

Here’s the Proof

  1. The impact of grape seed extract treatment on blood pressure changes
  2. Effects of grape seed extract beverage on blood pressure and metabolic indices in individuals with pre-hypertension: a randomised, double-blinded, two-arm, parallel, placebo-controlled trial.
  3. Proanthocyanidin-rich grape seed extract reduces leg swelling in healthy women during prolonged sitting.
  4. Grape seed proanthocyanidins extract promotes bone formation in rat's mandibular condyle.
  5. Formulation and evaluation on human skin of a water-in-oil emulsion containing Muscat hamburg black grape seed extract.
  6. Grape seed proanthocyanidin extract (GSPE) attenuates collagen-induced arthritis.
  7. Flavonoid-Based Therapies in the Early Management of Neurodegenerative Diseases
  8. Improvement in Memory and Brain Long-term Potentiation Deficits Due to Permanent Hypoperfusion/Ischemia by Grape Seed Extract in Rats.
  9. Wound-healing activity of the skin of the common grape (Vitis Vinifera) variant, Cabernet Sauvignon.
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About the author
Katie Hipwell - Katie is an AfN Registered Nutritionist (RNutr) with a specialism in food and is Head of Nutrition at Feel. Katie has worked in the food supplement industry for 10 years. She has completed a Master's degree in Human Nutrition and an undergraduate degree in BSc Sport and Exercise Nutrition.
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